Liverpool defeated Sparta Prague 6-1, scoring four goals in 14 minutes to advance to the Europa League quarterfinals. Meanwhile, Bundesliga leaders Bayer Leverkusen eliminated Qarabag with two stoppage goals.
West Ham, AC Milan, Roma, Marseille, and other teams were guaranteed a spot in Friday's quarterfinal draw.
Jurgen Klopp selected a surprisingly strong Liverpool team, and the Reds are still on track to win four titles, even though they led 5-1 after the first leg.
Bobby Clark, 19, and Darwin Nunez gave Klopp's team a strong start, and Mohamed Salah scored his 20th goal of the year to mark his first club start since January 1.
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Before Liverpool temporarily let up in preparation for their FA Cup trip to Manchester United on Sunday, Cody Gakpo scored the game's fourth goal.
Sparta's Veljko Birmancevic pulled one back, but Dominik Szoboszlai and Gakpo finished the massacre in the second half.
"It was an amazing win—and an amazing first 15 minutes," said Gakpo after the 11-2 aggregate victory.
"It's what we had in mind. It shows the confidence in the team at the moment."