With a 4-0 victory over struggling Everton on Wednesday, Arsenal surpassed Everton in the Premier League standings by five points. Gabriel Martinelli was the star of the match.
Late in the first half, Bukayo Saka defeated Everton's tenacious defence before Brazilian attacker Martinelli extended Arsenal's lead at the Emirates Stadium.
Martin Odegaard scored the third goal on a night that may go down as another watershed in Arsenal's ascent to the title. Martinelli completed the scoring to give Arsenal their most significant win since October.
As the title race nears its conclusion, Mikel Arteta's team needed to win to keep a game in hand over second-place Manchester City.
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The victory keeps Arsenal in a prime position to win the championship for the first time since Arsene Wenger's "Invincibles" in 2003-04 with 13 games remaining.
Arsenal has recovered impressively after stumbling through a stretch of three league games without a victory, which concluded with City overtaking them for first place with a 3-1 win at the Emirates.
Arsenal has won three games in a row since their loss to City, giving them 60 points, which ties their record-setting 2003-04 and 2007-08 seasons for their most outstanding point total after 25 Premier League games.
On February 4, Sean Dyche's tenure at Everton began with an unexpected 1-0 victory over Arsenal at Goodison Field.
However, Everton has only won once and lost three times since then, placing them third from the bottom of the standings.
Everton, who have only scored 17 goals this season, have played one more game than any of the bottom-dwelling teams in the league.
Everton is at serious risk of returning to for the first occasion since 1954, second tier unless Dyche can reverse their slump.
Leandro Trossard joined in attack instead of Eddie Nketiah, and Arteta got the answer for selecting the same lineup that won 1-0 at Leicester on Saturday.
After a brief corner nearly caught the visitors off guard, Jorginho shot over from inside the Everton area.
Aaron Ramsdale had to make two quick saves from Neal Maupay during a brief Everton pressure period, but neither of the striker's attempts had enough force to put the goalkeeper to the test.
The Slick Saka
Despite the Arsenal centre-back's physical altercation on the field after the Leicester match, Arteta had stated that things were "good" between Gabriel and William Saliba.
Gabriel undoubtedly appeared unmoved by the commotion when he slid across the field with a precisely timed block to deny Maupay from unleashing a shot.
Everton held off the opposition until Saka let loose the floodgates in the 40th minute.
Oleksandr Zinchenko set up the 21-year-old Saka in the Everton area. After holding off Vitaliy Mykolenko, he fired a ferocious shot, his eleventh goal, into the upper corner of the year.
Everton nearly immediately responded thanks to a long-range effort from Maupay that flew just wide.
Despite the escape, Arsenal was in fine form, and Martinelli extended their lead in the last seconds of the first half.
Martinelli scored this time after Saka stole the ball from a sleepy Idrissa Gueye and passed it to him. Following a VAR review for a close-range offside accusation against the Brazilian, the goal counted.
In the 71st minute, Odegaard put the outcome beyond question, beating Jordan Pickford with a deflected shot from Trossard's cross.
In the 80th minute, Martinelli knocked in Nketiah's cutback at the near post to give raging Arsenal a second goal.