Sevilla defeated Manchester United 3-0 on Thursday, eliminating them from the Europa League and advancing to the semifinals 5-2 overall.
After scoring two own goals in the first leg, Erik ten Hag's team continuously shot themselves in the foot and was outplayed by the record-breaking six-time winners.
Youssef En-Nesyri seized Harry Maguire's giveaway on the edge of his area to break the tie early on after he had already experienced one of those fateful moments.
Jose Luis Mendilibar's team earned their lead, which they skillfully guarded. Loic Bade headed in the second from a corner in the first few minutes of the second half.
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On a stormy night at the Ramon Sanchez Pizjuan stadium, En-Nesyri scored his second goal into an empty net after United goalkeeper David de Gea handed him the ball on a plate.
The Old Lady defeated Sporting Lisbon 2-1 on the road to the semifinals, where Sevilla will play Italian powerhouse Juventus.
Ten Hag called his team "unacceptable" and claimed they lacked the same zeal as their rivals.
Marcus Rashford and Luke Shaw, recovering from injuries, were also on the bench as Ten Hag was on the field.
Sevilla launched themselves into the game with incredible determination as the stadium rocked, and Maguire quickly rewarded them.
Due to the damage to Raphael Varane and Lisandro Martinez, Ten Hag was forced to start the Englishman at centre-back with Victor Lindelof.
Maguire appeared unconcerned by the three Sevilla players buzzing around him as he rolled the ball back to Spanish goalkeeper De Gea and called to receive it again from the goalie.
Former Tottenham winger Erik Lamela intercepted the ball as Maguire attempted to pass it, and En-Nesyri grabbed control of the play to beat De Gea at his near post.
While Bruno Fernandes was out on suspension, United made few noteworthy attempts to respond.
When Lucas Ocampos rammed home to energize the Pizjuan again, Sevilla believed they had scored a second goal, but VAR revealed a narrow offside on Marcos Acuna in the build-up.
In contrast to their local counterpart, which was fighting relegation, the hosts appeared every bit the Europa League experts their stellar record implies.
