Napoli got their first Serie A title in 33 years after drawing Udinese at Dacia Arena, sparking wild celebrations in Naples.
They won the tournament for the last time in 1990 when a Diego Maradona-inspired team added to their inaugural triumph three years earlier.
After Sandi Lovric gave Udinese the lead, Victor Osimhen equalized in the 52nd minute.
And Napoli claimed their third Serie A championship with five games to spare.
"Seeing Neapolitans delighted is enough to give you an idea of that joy they are feeling," Napoli manager Luciano Spalletti told DAZN.
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"You feel more at ease knowing you've given them this moment of joy."
Napoli's last two titles, in 1987 and 1990, were won during the reign of Argentina superstar Maradona, after whom their stadium is now called.
Following those glorious days, the team slipped into the financial downfall, relegation, and insolvency and was last seen in Serie C in 2006.
They have won the Coppa Italia thrice in the last 11 seasons, but the Scudetto is what Napoli fans have been waiting for.
They now have a new superstar lineup, with Nigeria striker Victor Osimhen scoring twenty-one goals in 26 league matches and Georgia winger Khvicha Kvaratskhelia adding 12 goals and ten assists.
Luciano Spalletti, who won the Coppa Italia twice with Roma, becomes the oldest coach to win Serie A at 64.
Last Saturday, his club had an opportunity to win the championship with six games to spare but instead drew with local rivals Salernitana.
However, with a 16-point lead over second-placed Lazio, their third Serie A title is already assured.