The Simpsons fans are buzzing again, convinced that the show has eerily predicted yet another real-life event.

Enthusiasts of the long-running Fox TV series have flocked to X to point out the latest 'coincidence' featured in the show.

Previously, The Simpsons has accurately forecasted surprising events such as the unexpected collaboration between Cypress Hill and the London Symphony Orchestra, mutant fish caused by water pollution, and even the 'Hawk Tuah' girl.

Now, a 2000 episode appears to have made another prescient prediction.

News emerged on Sunday afternoon that Joe Biden is stepping down from the upcoming US presidential election, prompting Republican candidate Donald Trump to swiftly respond on X with a sharp message.

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In Biden's announcement on social media, he strongly endorsed his current vice president, Kamala Harris, as the leading candidate for the Democratic party in the upcoming November election.

Fans quickly spotted a striking connection between Harris and The Simpsons, adding to the show's reputation for seemingly predicting the future.

In a 24-year-old episode of The Simpsons, Lisa Simpson, dressed in a purple suit, is shown being elected President 30 years into the future, following a tumultuous term under a President Donald Trump. The resemblance to Harris’s potential future candidacy has not gone unnoticed.

This specific episode from Season 11 has been frequently cited for its references to Donald Trump's rise and term as the 45th U.S. President from 2017 to 2021.

Fans have now noticed a peculiar detail: Lisa Simpson's purple suit in the episode bears a striking resemblance to the outfit worn by Kamala Harris during Joe Biden's inauguration as the 46th President in January 2021.

The resemblance between Harris's purple ensemble and Lisa's has ignited another wave of excitement online, as fans once again marvel at the show's uncanny predictions.

One user said: "Remember when Lisa was President of The United States on The Simpsons? Was that Kamala Harris?"

Another posted: "Not for nothing but the Simpsons already predicted this...."

A third shared: "The Simpsons has done it again! Here's from the 17th episode of the 11th season (in the year 2000) showing Lisa Simpson as the first female president of the United States talking about how the country is broke after President Trump. And, here's Kamala wearing the same outfit at Biden's inauguration."

Others begged the show to predict good fortunes in their future, but it turns out that it's not as carefully thought out as you might think.

The writer of the episode in question, Dan Greaney, spoke to The Hollywood Reporter in March 2016 about the 'warning' episode.